Created by Cirocco Dunlap, The Second Best Hospital In The Galaxy is an adult animated sci-fi comedy series from Prime Video.
The series is written by Cirocco Dunlap, Anne Lane, Joanna Bradley, Kirsten King, Shauna McGarry, and Asha Michelle Wilson.
Genre: Adult Animation, Science Fiction, Comedy
Release Date: February 23, 2024 (Season 1); May 27, 2025 (Season 2)
The series follows two best friends, Dr. Sleech (Hsu) and Dr. Klak (Palmer), as they deal with anxiety-eating parasites, inexorable time loops, and the depths of darkness.
Sleech and Klak are two intelligent female alien doctors who specialize in rare sci-fi illnesses in the Ergulon Galaxy.
Who Composed The Second Best Hospital In The Galaxy Score?
The original score for The Second Best Hospital In The Galaxy was composed by Wendy & Lisa — the duo of Wendy Melvoin and Lisa Coleman, longtime musical collaborators known for their television scoring work on Heroes, Dangerous Minds, Crossing Jordan, Nurse Jackie, Firefly Lane, and True Story. Their score for the series leans into a blend reminiscent of both science fiction and medical dramas, matching the show’s mix of cosmic weirdness and grounded emotional beats.
Important note: As of this update, no official standalone soundtrack album for The Second Best Hospital In The Galaxy has been released by Amazon MGM Studios or the composers. Fan-curated playlists exist on Spotify and YouTube collecting cues and needle-drops heard across both seasons, but these are unofficial compilations rather than a licensed release. We’ll update this page the moment an official album is announced.
Official Trailer: You can also watch the trailer of The Second Best Hospital In The Galaxy on YouTube, where you can get a glimpse of the series and its characters. (External Link: IMDB)
The Second Best Hospital In The Galaxy premiered on Prime Video on February 23, 2024, with all eight Season 1 episodes released together. A second season, also eight episodes, followed on May 27, 2025, bringing the series to 16 episodes total.
For those who like watching animated adventure series, this series is a good option because the animation, produced by Titmouse, Inc. with additional work from Copa Studio and Mighty Animation, has been praised for its distinctive, sealife-inspired alien designs.
The voice cast includes Stephanie Hsu (Dr. Sleech), Keke Palmer (Dr. Klak), Natasha Lyonne (Nurse Tup), Kieran Culkin (Dr. Plowp), Maya Rudolph (Dr. Vlam), Sam Smith (Dr. Azel), Andrew Dismukes (Matt), Gary Anthony Williams (Flork 1), and Lennon Parham (Flork 2).
The executive producers of the series include Cirocco Dunlap, Maya Rudolph, Natasha Lyonne, Danielle Renfrew Behrens, Shauna McGarry, Shannon Prynoski, Chris Prynoski, Antonio Canobbio, and Ben Kalina.
Quick Facts
| Title | The Second Best Hospital In The Galaxy |
| Composer | Wendy & Lisa (Wendy Melvoin & Lisa Coleman) |
| Release Date | February 23, 2024 (S1); May 27, 2025 (S2) |
| Genre | Adult Animation, Science Fiction, Comedy |
| Where to Watch | Prime Video |
| Where to Stream Music | No official soundtrack album released yet |
Frequently Asked Questions
Who composed the music for The Second Best Hospital In The Galaxy?
The score was composed by Wendy & Lisa (Wendy Melvoin and Lisa Coleman), known for their TV scoring work on Heroes, Dangerous Minds, Crossing Jordan, Nurse Jackie, and Firefly Lane.
Is there an official soundtrack album for The Second Best Hospital In The Galaxy?
No. As of this writing, no official standalone soundtrack album has been released. Only fan-made playlists exist on Spotify and YouTube.
How many seasons and episodes does the show have?
The series has two seasons totaling 16 episodes. Season 1 premiered February 23, 2024, and Season 2 premiered May 27, 2025, both on Prime Video.
Who stars in The Second Best Hospital In The Galaxy?
The voice cast includes Stephanie Hsu, Keke Palmer, Natasha Lyonne, Kieran Culkin, Maya Rudolph, and Sam Smith.
Where can I watch The Second Best Hospital In The Galaxy?
The series streams exclusively on Prime Video.
Related reading: Prime Video Soundtracks, More TV Soundtracks